Migration Groups: A Poorly Explored Point of View for Genetic Damage Assessment Using Comet Assay in Human Lymphocytes

A new point of view for genetic damage assessment using the comet assay is proposed based on number migration groups, comets in each group, and groups with highest comets. Human lymphocytes were exposed to different concentrations Methyl Methane Sulfonate (MMS), Maleic Hydrazide (MH), 2,4-Dichlorophenoxyacetic (2,4-D), N-nitroso diethylamine (NDEA). Using assay, means determined later grouped arbitrarily no higher differences than 1 µc. The (modes) determined. All four genotoxic agents studied showed a significant increase (p < 0.05) tail length compared negative control. did not show variation between four-genotoxic nor within their concentrations. However, comparison modes agents, but same agent, which indicated chemical interaction DNA. These parameters can improve detection associated certain agents.